Neuroimmune Interaction in Inflammatory Diseases

Neuroimmune Interaction in Inflammatory Diseases

The inflammatory response is modulated through interactions among the nervous, endocrine, and immune systems. Intercommunication between immune cells and the autonomic nervous system is a growing area of interest. Spatial and temporal information about inflammatory processes is relayed to the central nervous system (CNS) where neuroimmune modulation serves to control the extent and intensity of...

Editorial: Neuroimmune Interface in Health and Diseases

The neuroimmune basis of anti-inflammatory acupuncture.

This review article presents the evidence that the antiinflammatory actions of acupuncture are mediated via the reflexive central inhibition of the innate immune system. Both laboratory and clinical evidence have recently shown the existence of a negative feedback loop between the autonomic nervous system and the innate immunity. There is also experimental evidence that the electrical stimulati...

Gene-environment interaction modulated by allelic heterogeneity in inflammatory diseases.

CARD15 is a major susceptibility gene for a frequent multifactorial chronic inflammatory bowel disorder, Crohn disease (CD). By using NF-kappaB activation assays, the cytosolic CARD15 was shown to efficiently detect bacterial peptidoglycan (PGN), reminiscent of the PGN recognition protein surveillance mechanism in Drosophila. The 3 CD-associated variants and 13 additional variants carried by CD...

Peripheral blood smear in infection and inflammatory diseases

Peripheral blood smear study is very useful tool in early diagnosis of some infection and inflammatory diseases. In present article morphological changes of blood cells will be discussed in general infection and in viral infection such as HIV, H1N1 influenza and parvovirus B19. Physiologic and emergency granulopoesis will also be discussed.